Until recently, the only way to test for paternity while pregnant was to collect amniotic fluid via a long needle, which is an “invasive” procedure that presents a risk to the baby.
“Non-invasive” means there is no need to intrude in the baby’s safe environment to test for paternity.
A non-invasive prenatal paternity test is the safest way to determine fatherhood before the baby is born.
is an advanced non-invasive prenatal paternity testing for determining fatherhood.
Non-Invasive Prenatal Paternity Testing can be used to assess the paternity before the child is born.
PaternitySAFE™ allows to profile the baby’s DNA through the analysis of free-floating fetal DNA found in the mother’s blood, and subsequently to compare the baby’s profile to the one of the alleged father.
A groundbreaking sequencing technology (NGS) coupled with a sophisticated bioinformatic analysis
A simple buccal swab and a blood sample (3 ml) are required
Turnaround time of about 15 working days
Sensitivity and speciﬁcity >99%
During pregnancy, fetal DNA circulates naturally in maternal blood. Fetal DNA consists of short DNA fragments (~145/200 bp) present in plasma in variable percentage depending on the gestational period and can be detected from 5 weeks gestational age; its concentration increases in the following weeks and from the 9°-10° week of gestation it’s possible to perform the test ensuring the highest sensitivity and specificity.
The test is performed by taking a blood sample from the mother with a gestational age of at least 9 weeks. Thanks to a complex laboratory analysis, cell-free DNA is isolated from maternal plasma and then sequenced using Next Generation Sequencing (NGS) technique and subsequently compared to the alleged father’s DNA which is collected using a simple buccal swab.
The baby’s genetic profile will be made up of half of the genetic profile from the mother and half from the father. Therefore, the alleged father to be considered the biological father will have to own half of the genetic profile present in the baby. Paternity is EXCLUDED in case in which the genetic characteristics of the putative father differ from those of the baby, while it is ATTRIBUTED if they match.
At the end of the process a report is generated to show if the man tested is or is not the biological father.
showed an analytical sensitivity and specificity >99.9% in validation studies.
Great reliability of the results
The alleged father cannot be excluded as the biological father. In this case, the tested male is the biological father and we will confirm this with a Probability of Paternity >99.9%.
The alleged father is excluded as the biological father of the fetus. The tested alleged father is excluded as the biological father of the unborn baby. We will exclude him with a 100% probability (Probability of Paternity: 0%).
PaternitySAFE™ Forms and Brochures
PaternitySAFE™ Sample lab reports
From over 20 years, Genoma has been the leading pioneer in genetic testing.
Our team’s unmatched knowledge and experience deliver a combination of advanced technology
and deep patient data sets that lead to more accurate diagnosis.
in Italy (Milan or Rome)
20 years experience in prenatal molecular diagnostics
with groundbreaking technologies
about 15 working days
Team of experts
Dedicated R&D team
Numerous peer-reviewed papers published in renowned international journals
Ordering PaternitySAFE™ test is simple and fast
Contact us by calling the Contact Center at +39 06164161500 to discover how you can perform PaternitySAFE™ test or fill out the form below. Your personal information will be used exclusively to satisfy your request, in the absolute respect of your privacy.