Non-invasive Prenatal Paternity Testing

Until recently, the only way to test for paternity while pregnant was to collect amniotic fluid via a long needle, which is an “invasive” procedure that presents a risk to the baby.

“Non-invasive” means there is no need to intrude in the baby’s safe environment to test for paternity.
A non-invasive prenatal paternity test is the safest way to determine fatherhood before the baby is born.

paternitySAFE
is an advanced non-invasive prenatal paternity testing for determining fatherhood.

Non-Invasive Prenatal Paternity Testing can be used to assess the paternity before the child is born.
PaternitySAFE allows to profile the baby’s DNA through the analysis of free-floating fetal DNA found in the mother’s blood, and subsequently to compare the baby’s profile to the one of the alleged father.

ADVANCED

A groundbreaking sequencing technology (NGS) coupled with a sophisticated bioinformatic analysis

NON-INVASIVE

A simple buccal swab and a blood sample (3 ml) are required

FAST

Turnaround time of about 15 working days

ACCURATE

Sensitivity and specificity >99%


During pregnancy, fetal DNA circulates naturally in maternal blood. Fetal DNA consists of short DNA fragments (~145/200 bp) present in plasma in variable percentage depending on the gestational period and can be detected from 5 weeks gestational age; its concentration increases in the following weeks and from the 9°-10° week of gestation it’s possible to perform the test ensuring the highest sensitivity and specificity.

The test is performed by taking a blood sample from the mother with a gestational age of at least 9 weeks. Thanks to a complex laboratory analysis, cell-free DNA is isolated from maternal plasma and then sequenced using Next Generation Sequencing (NGS) technique and subsequently compared to the alleged father’s DNA which is collected using a simple buccal swab.

The baby’s genetic profile will be made up of half of the genetic profile from the mother and half from the father. Therefore, the alleged father to be considered the biological father will have to own half of the genetic profile present in the baby. Paternity is EXCLUDED in case in which the genetic characteristics of the putative father differ from those of the baby, while it is ATTRIBUTED if they match.

At the end of the process a report is generated to show if the man tested is or is not the biological father.

-
paternitySAFE

showed an analytical sensitivity and specificity >99.9% in validation studies.

Great reliability of the results

Paternity attributionPaternity attribution

The alleged father cannot be excluded as the biological father.

Paternity exclusionPaternity exclusion

The alleged father is excluded as the biological father of the fetus.



ORDER THE PATERNITYSAFE COLLECTION KIT

FILL IN ALL REQUIRED TRF INFORMATION AND ENCLOSE THE INFORMED CONSENT SIGNED FROM THE PATIENT

COLLECT DNA SAMPLES THROUGH A SIMPLE BLOOD SAMPLE (MOTHER) AND A BUCCAL SWAB (ALLEGED FATHER)

SHIP THE SAMPLES TO EUROFINS GENOMA LAB

RECEIVE RESULTS

From over 20 years, Eurofins Genoma has been the leading pioneer in genetic testing.
Our team’s unmatched knowledge and experience deliver a combination of advanced technology and deep patient data sets that lead to more accurate diagnosis.

Test performed
in Italy (Milan or Rome)

20 years experience in prenatal molecular diagnostics

3 Laboratories
with groundbreaking technologies

Over 200.000
genetic tests/year

Fast TAT:
about 15 working days

Team of experts
in genetics

Test available
worldwide

Dedicated R&D team
Numerous peer-reviewed papers published in renowned international journals

Ordering PaternitySAFE test is simple and fast

Contact us by calling the Contact Center at +39 06164161500 to discover how you can perform PaternitySAFE test or fill out the form below. Your personal information will be used exclusively to satisfy your request, in the absolute respect of your privacy.

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ROME
Diagnostic Lab and Genetic Counselling
Via Castel Giubileo, 62 - 00138 Rome (RM)
R&D Laboratory
Via Castel Giubileo, 11 - 00138 Rome (RM)
Contact Center: +3906164161500 (12 lines PBX)
Fax : +390664492025
E-mail info@laboratoriogenoma.eu

MILAN
Diagnostic Lab and Genetic Counselling
Via Enrico Cialdini, 16 (Affori Centre) - 20161 Milan (MI)
Contact Center: + (39) 02.39297626 (12 lines PBX)
Fax : +390239297627
E-mail info@genomamilano.it
E-mail
info@laboratoriogenoma.eu

Website
http://www.laboratoriogenoma.eu

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